JXL069 MPC Inhibitor (50mg Powder) – Research Use Only

JXL069 (also known as JXL‑069) is a small molecule that affects cellular energy balance by altering pyruvate flux. In research settings, it has been shown to modulate pathways linked to hair follicle stem cell activation in preclinical mouse models. While these studies are early‑stage, they suggest JXL069 could be a valuable research tool in exploring the biology of hair regrowth** and metabolic signaling.

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Description

Packages halted at customs will be reshipped for free. Please allow 4-5 weeks after order for delivery.

Small batches reasonably priced from our lab in China.

JXL069 is a potent and selective inhibitor of the mitochondrial pyruvate carrier (MPC). By blocking pyruvate transport into mitochondria, JXL069 shifts cells from oxidative metabolism toward glycolysis, altering the cellular energy balance. In preclinical research models, this metabolic shift has been linked to activation of hair follicle stem cells and enhanced hair cycling, making JXL069 a compound of interest in studies focused on regenerative pathways, alopecia models, and cellular metabolism.

This compound is intended strictly for laboratory research use and is not for human or veterinary applications. Any mention of biological activity is based on published research and does not imply approval for therapeutic, diagnostic, or cosmetic use.


Storage Conditions

  • Powder: –20 °C (stable for up to 3 years), 4 °C (2 years)

  • Solution: –80 °C (6 months), –20 °C (1 month)

  • Avoid repeated freeze–thaw cycles

Shipping

Shipped under ambient temperature as a non‑hazardous chemical. The product remains stable during routine shipping and customs handling.

Solubility & Formulation

  • Soluble in DMSO (gentle heating or sonication may assist)

  • Stock solutions should be aliquoted to reduce freeze–thaw cycles

Technical Data

  • Synonyms: JXL069; JXL‑069

  • IUPAC: (E)-3-(1-(3,5-bis(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)-2-cyanoacrylic acid

  • Purity: >98% (see Certificate of Analysis)

  • Appearance: Solid powder

  • Shelf Life: >2 years if stored properly

Additional information

Milligram

25mg, 50mg, 100 mg, 150 mg, 200 mg, 250 mg, 300 mg, 500 mg, 1000mg (1g)

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